Zamperk are large, powerful creatures related to ancient dragons, but classified as a modern hydra. They are covered in thick dragon scales made of opaque crystals and have large, razor-sharp claws and teeth. They have long, whip-like tails with an accelerated regeneration factor that often not only heals all cuts and wounds, but also spawns additional, conjoined zamperk bodies as appendages. Zamperk scales are a common medicinal component when ground up into fine powder.

Zamperks can also be found hibernating in large caves, particularly those found inset in mountainous terrain. Zamperks sometimes sleep for years at a time and are very difficult to wake up; however, whenever a zamperk awakens, they experience intense hunger and will hunt down the first living thing they see.